Tudor-SN Interacts with Piwi Antagonistically in Regulating Spermatogenesis but Synergistically in Silencing Transposons in Drosophila.
Piwi proteins associate with piRNAs and functions in epigenetic programming, post-transcriptional regulation, transposon silencing, and germline development.However, it is not known whether the diverse functions of these proteins are molecularly separable.Here we report that Piwi interacts with Tudor-SN (Tudor staphylococcal nuclease, TSN) antagoni